Putative periodontal pathogens in the subgingival plaque of Sudanese subjects with aggressive periodontitis.

Hashim, N T and Linden, G J and Winning, L and Ibrahim, M E and Gismalla, B G and Lundy, F T and El Karim, I A (2017) Putative periodontal pathogens in the subgingival plaque of Sudanese subjects with aggressive periodontitis. Archives of oral biology, 81. pp. 97-102. ISSN 1879-1506

Full text not available from this repository.

Abstract

BACKGROUND AND OBJECTIVES There has been limited study of the bacterial species associated with aggressive periodontitis (AgP) in high-risk populations in Africa. The aim of this study was to investigate and quantify the presence of four putative periodontal pathogens in the subgingival plaque of Sudanese subjects with AgP. A secondary aim was to investigate the effect of varying the detection threshold on the reported prevalence of the bacterial species investigated. MATERIALS AND METHODS Subgingival plaque samples were collected from AgP cases (n=73) and healthy controls (n=71). Bacterial DNA was extracted and analyzed by quantitative polymerase chain reaction for the detection and quantification of four putative periodontal pathogens: Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, Treponema denticola and Tannerella forsythia. RESULTS At the lowest detection threshold (>101 cells), P. gingivalis (p<0.0001) was more prevalent in AgP cases than controls. T. forsythia and T. denticola had a high prevalence (>70%) in AgP cases at all detection levels. While T. forsythia was significantly more frequently identified in AgP than in controls at all detection thresholds, this was only the case for T. denticola at the intermediate threshold (>102 cells). A. actinomycetemcomitans was identified less frequently than the other bacterial species with no difference in its prevalence between AgP cases and controls. CONCLUSION The prevalence of the putative periodontal pathogens investigated varied considerably in Sudanese subjects with AgP and in periodontally healthy controls depending on the detection thresholds applied. T. forsythia was identified as having the strongest association with AgP.

Item Type: Article
Subjects: Q Science > QR Microbiology
Depositing User: Moneeb Hassan
Date Deposited: 14 Jan 2018 19:11
Last Modified: 14 Jan 2018 19:11
URI: http://search.srh.edu.sd/id/eprint/3048

Actions (login required)

View Item View Item