No Reduction in Hemoglobin Level in Severe Plasmodium falciparum Malaria Treated with Artesunate in Central Sudan.

Eltahir, Hatim G and Bilal, Jalal Ali and Ali, Elrazy A and Adam, Ishag (2017) No Reduction in Hemoglobin Level in Severe Plasmodium falciparum Malaria Treated with Artesunate in Central Sudan. Journal of tropical pediatrics, 63 (1). pp. 18-22. ISSN 1465-3664

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Abstract

BACKGROUND There are few publications on anemia following artesunate treatment. OBJECTIVE To investigate the hemoglobin in patients with severe Plasmodium falciparum malaria treated with artesunate or quinine. METHODS Patients with P. falciparum (in Singa, Sudan) were treated by intravenous artesunate or quinine. Hemoglobin was measured initially, at day 14 and day 28. RESULTS The mean (SD) of the age was 10.3 (10.9) years. The two groups (61 in each arm) were matched in their basic characteristics. Hypotension, convulsions, severe anemia were the main presentations. There was no significant difference in the mean (SD) hemoglobin level at the initial day, day 14 and at day 28 [11.2 (1.8), 11.3 (1.6), 11.5 (1.8), p = 0.170], respectively, in both groups. The hemoglobin did not change significantly from the baseline in any of the group separately. CONCLUSION There was no difference in hemoglobin concentration in patients with severe malaria after treatment with either artesunate or quinine.

Item Type: Article
Subjects: R Medicine > RG Gynecology and obstetrics
Depositing User: Prof Ishag Adam
Date Deposited: 06 Jan 2018 19:30
Last Modified: 06 Jan 2018 19:30
URI: http://search.srh.edu.sd/id/eprint/700

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